Myra, Kathryn, Alexis, Isabelle, Nikki and Anna seek justice for Yoko Akia, a young florist. Yoko wants to punish her father, who bought, impregnated and discarded her teenage mother, who died after giving birth to her. The lethal ladies are shocked to discover Yoko's dad is none other than Michael Lyons, an award-winning film star with another nasty secret: he's been buying and selling Asian women as sex slaves to prominent businessmen. The Sisterhood's fearless male cohorts, notably Myra's pal, Charles Martin, a former British secret agent, lend assistance, but in the end the female vigilantes must confront Lyons in L.A. on their own with two nosy reporters hot on their trail.